Oxidative stress, metabolic dysfunction, and neuroinflammation are well-known hallmarks of ALS, which gave the researchers a target for their quest to understand the disease: a group of enzymes called ...
Familial ALS (FALS) runs in families. About 5% to 10% of people with amyotrophic lateral sclerosis have this type. Changes to a gene cause FALS. Parents pass the faulty gene to their children.