Since then, many scientists, including Lu, who now leads his own research group at Western University, have shown that PIN1 is overexpressed in different types of cancer and regulates many oncogenes ...

Faulty lipid regulation in CLL patients impairs T-cell function, affecting treatment outcomes and resistance to current therapies. Differences in lipid metabolism between CLL patients and healthy ...

A new study from Washington University School of Medicine in St. Louis identifies a possible way to slow or block progression of age-related macular degeneration, a leading cause of blindness in ...

B cell activation and antibody class switching requires coordinated metabolic rewiring, with essential roles for amino acid transport, cholesterol metabolism, and prenylation in driving proliferation ...

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. Published in the ...

In a recent review published in the journal Experimental & Molecular Medicine, researchers reviewed available literature on the role and mechanisms (molecular and pathological) by which cholesterol ...

Cholesterol is a waxy substance in your blood. Your body needs cholesterol to build healthy cells. Having too much cholesterol can increase your risk of heart disease. When you have high cholesterol, ...