Chromatin structure is highly complex and impressively ... more directly with DNA and the different proteins within the nucleus. Because eukaryotic DNA is tightly wrapped around nucleosomes ...
5 Chromatin segments found at loop junctions are in such close ... One hypothesis is that the DNA loops could determine which genes are switched on in the cell. Inside a nucleus, chromosomes jumble ...
The unexpected discovery may provide scientists with new insights into how cancer develops — and how to combat it.
Yeast also has the same way of organizing chromosomes, while in humans and other mammals, each chromosome occupies its own specific region in the nucleus. "If we look at the average chromatin ...
system enables precise manipulation of chromatin loci. By inducing synthetic liquid-like droplets within the cell’s nucleus using a specific wavelength of blue light, researchers can apply ...
Compared to its sequence, relatively little is known about the structure of the human genome, which enables more than two meters of chromatin to fit inside the nucleus. Chromosomes are thought to be ...
To fit such a long molecule within the tiny space of the nucleus, DNA bends and loops in several ways. The largest of these loops results from the helical coiling of chromatin (the thick line in ...
Histones are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin. Nuclear DNA does not appear in free linear strands; it is highly condensed and ...
In eukaryotes, genomic DNA is stored in the nucleus as nucleosomes, interacting with a set of proteins, forming a molecular complex called chromatin. The proper folding of the chromatin structure ...
Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell ...
Moreover, we observed that expression of a chromatin regulator from an mRNA with or without its 3′UTR resulted in similar expression of the protein in the nucleus but changed the enzymatic activity of ...
2. The resting nucleus consists of delicate chromatin threads or meshes, with some nodelike structures at the intersections of the threads. 3. The first indication that reduction is about to take ...