Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...

5 Chromatin segments found at loop junctions are in such close ... One hypothesis is that the DNA loops could determine which genes are switched on in the cell. Inside a nucleus, chromosomes jumble ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

Chromatin structure is highly complex and impressively ... more directly with DNA and the different proteins within the nucleus. Because eukaryotic DNA is tightly wrapped around nucleosomes ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...

During interphase, individual chromosomes are not visible, and the chromatin appears diffuse ... occupy specific territories within the nucleus (Cremer & Cremer, 2001). In any case, as mitosis ...

Compared to its sequence, relatively little is known about the structure of the human genome, which enables more than two meters of chromatin to fit inside the nucleus. Chromosomes are thought to be ...

How chromatin openness controls behavioral changes remains unclear. This work implicates alternative promoter selection, ...

Moreover, we observed that expression of a chromatin regulator from an mRNA with or without its 3′UTR resulted in similar expression of the protein in the nucleus but changed the enzymatic activity of ...

A novel technique to visualize gene-active and gene-repressive DNA regions in living cells, developed by a ...