Scientists at EMBL have captured how human chromosomes fold into their signature rod shape during cell division, using a ...

Compared to its sequence, relatively little is known about the structure of the human genome, which enables more than two meters of chromatin to fit inside the nucleus. Chromosomes are thought to be ...

The largest of these loops results from the helical coiling of chromatin (the thick line in this illustration). This coiling causes the chromosome to resemble a spring. Chromatin refers to ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

“This is the first study using this model of replicative senescence to define those higher-order three-dimensional chromatin changes,” said epigeneticist Peter Adams of the Cancer Research UK Beatson ...

Chromosomes that lack centromeres segregate ... scientists now know that each centromere is a region of highly specialized chromatin. Although significant differences have been found in the ...

Bringing together the genetic and cytological data, Lyon interpreted "sex chromatin" to be a manifestation of a genetically inactive X chromosome. She could then explain the mottled appearance of ...

Thus, in the reconstruction of the four daughter nuclei, two of them contain more chromatin than the other two. The resulting pollen grains, however, look alike. 14. In the somatic mitosis there are ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have ...

Chromosomes also play a role in regulating gene expression. The structure and packaging of chromatin can influence which genes are active or silenced in a particular cell type or developmental stage.

demonstrated that chromosome segregation errors alter the shape of the nucleus as well as its mechanical properties. The shape and mechanics of the nucleus are known to be influenced by internal ...