However, as in the case of PROTACs, because autophagy occurs in the cytoplasm, the current technologies are restricted to cytosolic proteins. To overcome this limitation, the authors explored the ...
Figure 3: Import of matrix proteins into peroxisomes. Cargo-loaded PTS1 and PTS2 receptors dock to the cytosolic surface of the peroxisomal membrane to initiate the cascade of peroxin-mediated ...
promoting normal or improved cellular protein quality control by increasing expression of thiol transferases in affected cells effective for manipulating endoplasmic reticulum (ER) and cytosolic ...
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