Single-Stranded DNA The molecule of the hereditary material deoxyribonucleic acid (DNA) normally consists of two interwoven strands. The discovery of a form with only one strand promises to ...

This process mends breaks ... mutated DNA repair genes to assess a person’s risk of related cancers. Dynamic single-molecule analysis revealed that the BRCA2 protein binds to double stranded ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

The native structure of genomic DNA can be damaged in many ... nucleotide excision repair; pol η, polymerase η; SSB, single-strand break; TCR, transcription-coupled repair.

A number of these disorders have a definitive link to an inherited or acquired defect in one of the DNA repair ... excision repair; pol η, polymerase η; SSB, single-strand break; TCR ...