The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

Due to their activation by growth factors ... All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. Journal of Biological Chemistry 271, 5251–5257 ...

Topical BRAF inhibitor LUT014 gel significantly reduces acneiform rash from anti-EGFR therapies in patients with colorectal ...

The key role nanodomains play in regulating the activity of the epidermal growth factor receptor (EGFR)—a protein ... "The PI(4,5)P 2 nanodomain supports EGFR activation, while activated EGFR ...

Bicara Therapeutics shows potential to reshape cancer care with ficerafusp alfa and robust funding post-IPO. Find out why ...

Although many ecDNA-encoded oncogenes and their protein products, such as epidermal growth factor receptor (EGFR ... of telomeric length, or the activation of an oncogene can lead to genome ...

AstraZeneca, a global biopharmaceutical company is in collaboration with Revna Biosciences (www.RevnaBio.com), a precision medicine research and advanced diagnostics company to provide EGFR (Epidermal ...

CytomX Therapeutics, Inc.’s CTMX share price has surged by 6.39%, which has investors questioning if this is right time to ...

Apollomics and LaunXP have signed an agreement to develop and commercialise the former’s c-Met inhibitor vebreltinib combined with an epidermal growth factor receptor inhibitor (EGFRi ...

BCs can be further classified into three subtypes, based on their molecular identifications: Estrogen Receptor alpha (ERα)-positive, Her2 (human epidermal growth factor ... ERα is a hormone-activated ...