This creates a second “skeleton” of extra bone, which makes movement impossible. There is no ethnic, racial, gender or geographic predilection for FOP and children who have the condition ...
The genetic twist that leads to FOP, is relevant to every condition that affects the formation of bone and every condition that affects the formation of the skeleton,' said Dr. Frederick Kaplan ...
FOP is caused by a mutation in a gene known as ACVR1, which is involved in a cellular process that regulates the skeleton's development in the womb and repairs the skeleton throughout life.