Altered lipid metabolism in homozygous familial hypercholesterolemia relevant to drug treatment. Reduced LDL receptor function, but with up to 75% having residual activity of between 2 and 25% ...

Cholesterol is measured with a simple blood test called a lipid panel or lipid profile ... such as those diagnosed with familial hypercholesterolemia or those have already had a heart attack ...

Currently available lipid ... acceptable safety profile. The ODYSSEY program studies alirocumab in the following patient populations: • patients with Heterozygous Familial Hypercholesterolemia ...

The guidelines recommend the first lipid profile at the age of 18, or earlier with a positive family history of premature heart disease or familial hypercholesterolemia. The general population and ...

The purpose of this review is to summarize the current pharmacological treatment options for the treatment of hypercholesterolemia ... benefit of shifting the lipid profile toward a less ...

Verve Therapeutics has generated evidence its PCSK9 pivot could pay off. | Verve Therapeutics has generated evidence its ...