Here, we report using novel conditionally immortalized human podocytes in vitro and human ... Conditionally immortalized human glomerular endothelial cells do not respond to insulin, suggesting ...

The glomerular filtration barrier, from the blood to the urinary space, consists of endothelial cells, a basement membrane and specialized epithelial cells called podocytes. Endothelial cells have ...

glomerular endothelial cells (GEnCs), the glomerular basement membrane, and podocytes. GEnCs line the inner surface of the ...

Filtration is dependent on the unique structure of the capillary wall comprising layers of two key cells types, glomerular endothelial cells (GEnC) and podocytes, separated by a specialised basement ...

Podocytes are highly specialised, terminally differentiated cells with a complex cellular architecture. They are a critical component of glomerular filtration. Cell-cycle control, growth arrest and ...

is a progressive disease characterized by damage to the glomerular filtration barrier (GFB), the loss of larger and essential proteins from the blood into the urine (proteinuria), causing considerable ...

It examines the impact of mTOR on podocytes, glomerular mesangial cells, renal tubular epithelial cells, and glomerular endothelial cells—each playing a crucial role in kidney function.

A hallmark of DN is the thickening of the glomerular basement membrane (GBM ... balance of COL4 in the kidney's filtering cells (podocytes). Researchers identified GPR107 as a key regulator ...

A hallmark of DN is the thickening of the glomerular basement membrane (GBM ... balance of COL4 in the kidney's filtering cells (podocytes). Researchers identified GPR107 as a key regulator ...