… the toad, ugly and venomous, Wears yet a precious jewel in its head. Shakespeare’s contemporaries carried on their persons, usually in rings, certain “stones” cut from the heads of big, old toads.

In an unusual turn for an unassuming species, a desert amphibian is at the center of both a potential ecological crisis and an evolving question of drug policy. The creature in question is the ...

Hallucinogenic compounds that activate multiple receptors, found in Colorado River toads, show “promising transdiagnostic therapeutic with rapid and lasting effects” for conditions such as depression ...