Current standard modalities for detecting and quantifying monoclonal immunoglobin in patients with cold agglutinin disease lack adequate sensitivity. Heavy chain/light chain assay may be more ...
A γ 1 protein, designated CRA, found in heavy chain disease contains three inter-heavy disulfide bridges instead of the two normally found in γ 1 immunoglobulin heavy chains. Almost the entire Fd ...
In approximately one-third of patients with MIDD the underlying clone of monoclonal plasma cells cannot be routinely detected. 2 However, recent availability of serum free light chain (FLC) assay has ...
In a recent study published in the journal Nature, researchers investigate whether pairs of unrelated B-cells of naive, unswitched, memory and plasmablast phenotypes that have similar heavy chains ...
A new study published on the online preprint server bioRxiv* in May 2020 reports the construction and testing of a new ferritin-based antigen-bearing protein that has biological activity towards the ...
Genetic variants in MDR1 and CYP3A5 and vincristine toxicity in children with acute lymphoblastic leukemia. Background: Children and adolescents diagnosed with mature B-NHL have an excellent prognosis ...
Numerous conditions cause albuminuria. Various B-cell lymphoproliferative disorders have been associated with Bence Jones proteinuria. However, only two related conditions are associated with the ...
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