In particular, microtubules from one side of the spindle attach to one of the chromosomes in each homologous pair ... thanks to recombination during meiosis I. Meiosis is important because ...

One of the most notable examples of recombination takes place during meiosis (specifically, during prophase I), when homologous chromosomes line up in pairs and swap segments of DNA. This process ...

During gestation, primordial germ cells replicate their DNA and pair up homologous chromosomes for homologous recombination. Meiosis is then arrested until ovulation many years later. Just before ...

The human body is made up of billions of cells. These cells grow and divide through a process called cell division. There are ...

In Meiosis I homologous chromosomes separate, which requires pairing, synapsis, and recombination. In Meiosis II sister chromatids segregate from each other similarly to mitosis. Meiotic events must ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...

Our group is also interested in understanding the mechanism and regulation of homologous recombination during meiosis initiated by DNA DSBs mediated by the Spo11 protein together with a suite of ...