Numerous studies have suggested the cultivation of cells derived from intestinal organoids as two-dimensional (2D) monolayers ...

Researchers at the Francis Crick Institute have shown that the Cryptosporidium parasite exports a protein into infected ...

Mammalian intestinal epithelium is one of the most swiftly self-renewing tissues in the body, turning over completely every 3 to 5 days. Because of the absence of reliable stem cell markers, however, ...

More information: Alison R. S. Pashos et al, H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium, Nature Cell Biology (2025). DOI: 10.1038/s41556-024-01580-y ...

difficile infection. The white areas show the cells that line the intestine (epithelial cells). In red is the MHC-II protein, which helps activate the immune system, and in blue is the nucleus of ...

difficile infection. The white areas show the cells that line the intestine (epithelial cells). In red is the MHC-II protein, which helps activate the immune system, and in blue is the nucleus of ...

Fachi et al, Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection, Cell Host & Microbe (2025). DOI: 10.1016/j.chom.