Since their effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their anesthetic ...

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their ...

Not many drugs are as widely used yet poorly understood as anesthetics. “We’ve used them for over a century, but nobody understands how they work,” says Alex Proekt, an anesthesiologist and ...

Newborn mice experienced apoptotic cell death after exposure to the anesthetic agent isoflurane, according to a study published in Anesthesia-Analgesia. Researchers from the University of Cincinnati’s ...

Researchers from Switzerland's Institute for Research in Biomedicine have demonstrated the necessity of both anesthetic choice and vital monitoring during anesthesia use with experimental animals.