Kinesin-5 slides antiparallel microtubules during spindle assembly, and regulates the branching of growing axons. Besides the mechanical activities enabled by its tetrameric configuration, the ...

Kinesins are biological motor proteins that are ATP-dependent and function to assist cells with the transport of molecules along microtubules. Simply put, these proteins, function as highways within ...

Figure 1: Structure and motility models of KIF5 and KIF1A. The kinesin motor domain is composed of a single globular catalytic core and a short strand 'neck linker'. The catalytic core contains both ...

The structure of a key part of the machinery that allows cells to divide has been identified by researchers, opening new possibilities for throwing a wrench in the machine and blocking runaway cell ...

Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks. This miniature highway system is vital for keeping neurons healthy: ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...

Learn more about an important cellular protein called kinesin from this video by the University of California San Francisco (UCSF), and Ron Vale Ph.D., a UCSF researcher. Kinesin is a motor protein, ...

Inside mammalian cells, kinesin plays the same role as do trucks and locomotives within our countries: it is the main driving force behind the transport of manufactured goods. No wheels are involved, ...

The molecular mechanism that ensures cellular cargo is transported along the right track has been identified ...

This is a preview. Log in through your library . Abstract Kinesin I can walk on a microtubule for distances as long as several micrometers. However, it is still unclear how this molecular motor can ...

One of the hallmarks of cancer is the uncontrolled growth of cells that leads to tumours forming. Using chemotherapy that disrupts the machinery needed for cell division is commonly used to tackle ...

The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a wrench in ...