Chronic lymphocytic leukemia (CLL) is a slow-growing cancer that affects white blood cells. Survival rates tend to be high, but these may vary. Leukemia is a type of cancer involving human blood ...

Apr. 3, 2025 — Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers ...

The three-dimensional structure of DNA in the nucleus is stabilized ... architecture to drive gene regulation in acute ...

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that ...

In aggressive cases of leukemia, the only chance ... to a cytotoxic drug recognize all blood cells in the patient's body based on a surface structure. This marker is common to all the different ...

Bioinformatics and experimental validation have revealed 179 shared differentially expressed genes (DEGs) between chronic lymphocytic leukemia (CLL) and diffuse large B-cell lymphoma (DLBCL), ...

Although definitive treatment for acute leukemia involves chemotherapy, leukapheresis—to urgently reduce dangerously elevated white blood cell counts—is a potentially life-saving therapeutic ...

Using human T cells and leukemia cells in specialized mouse models, researchers developed the novel ALA-CART cells which showed promising results in fighting acute lymphocytic leukemias that were ...

After 72 hours, the aptamer alone had reduced the cancer cells in culture by 40%, demonstrating the aptamer's toxicity to the cancer, the researchers report. When the aptamers carried the leukemia ...

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers -- short single ...