APOBEC3 enzymes’ main role is to induce mutations in viral RNA and DNA that stop pathogenic viruses from ... and most mutations are just passengers—suggesting that APOBEC3 mutations may not affect ...

Most cancer therapies that target specific mutations are designed to inhibit pathogenic proteins that arise from mutated oncogenes, and most synonymous mutations probably don’t affect the structure of ...

In the realm of oncology, genetic mutations are well-established as pivotal factors predisposing individuals to various cancers. Particularly, germline ...

Most cancer genome studies have focused on mutations in the tumor itself and how such gene variants allow a tumor to grow unchecked. A new study, led by researchers at Washington University School ...

Most cancer genome studies have focused on mutations in the tumor itself and how such gene variants allow a tumor to grow unchecked. A new study, led by researchers at Washington University School ...

Researchers have made significant advancements in understanding the earliest stages of stomach cancer, a leading cause of cancer-related deaths worldwide, through two recent innovative studies.

The researchers examined data between 2018 and 2022. Blood sample tests revealed that 104 patients (14%) had KRAS ctDNA ...

Inherited mutations in the gene BRCA2 significantly increase the risk ... resulting in uncontrolled cell division and, in some circumstances, cancer development. BRCA2 predisposes carriers to cancer ...