Neuropeptide Y (NPY) receptors play important roles in appetite regulation. Many efforts have been made to develop drugs to treat obesity by regulating this system. However, the drug discovery is ...

Pancreatic cancer is still among the most lethal cancers, with >45% of patients presenting distant metastasis at diagnosis, and with a 5-year survival rate of 13%. Known for its role in appetite and ...

Transitions between life-history stages are often accompanied by dramatic behavioral switches that result from a shift in motivation to pursue one resource over another. While the neuroendocrine ...

Jens Meiler's team determined the first crystal structure for a neuropeptide Y receptor, deciphering the thousands of carbon, oxygen, nitrogen and other atoms involved with it and how they bind to one ...