A novel mechanism has been identified for how stress-induced anxiety -- which can produce post-traumatic stress disorder, or PTSD -- affects circuit function in the hippocampus, the area of the brain ...

Neuropeptide Y (NPY) is a self-produced molecule in the brain that has robust anxiety-relieving effects. New research on mice suggests that acute stress blocks the endogenous production of NPY and ...

Prior animal research showed an association between the neuropeptide Y (NPY) pathway and its three receptor genes and alcohol dependence, alcohol withdrawal and cocaine use. New human findings link ...

Neuropeptide Y exhibits neuroprotective effects. Whether the neuroprotective effects are mediated by the pathways including regulating the immunological activity of reactive microglia and reducing ...

Neuropeptide Y (NPY) receptors play important roles in appetite regulation. Many efforts have been made to develop drugs to treat obesity by regulating this system. However, the drug discovery is ...

Neuropeptide Y (NPY) is a 36-amino acid peptide that is widely distributed in the central nervous system (CNS). Intracerebroventricular (ICV) administration of NPY stimulates food intake (Clark et al.

Transitions between life-history stages are often accompanied by dramatic behavioral switches that result from a shift in motivation to pursue one resource over another. While the neuroendocrine ...

Pancreatic cancer is still among the most lethal cancers, with >45% of patients presenting distant metastasis at diagnosis, and with a 5-year survival rate of 13%. Known for its role in appetite and ...

Neuropeptide Y exhibits neuroprotective effects. But the neuroprotective effects that are mediated by the pathways including regulating the immunological activity of reactive microglia and reducing ...

Researchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolism 'switch' to help it spread, revealing a potential new treatment strategy for ...