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The RNA-binding protein Cpeb4 is a novel positive regulator of osteoclast differentiation. Biochemical and Biophysical Research Communications , 2020; DOI: 10.1016/j.bbrc.2020.05.089 Cite This Page : ...
Targeting osteoclast differentiation is therefore, a potential therapeutic strategy. In a new study, researchers have discovered a novel role of the Ctdnep1 phosphatase in suppressing osteoclast ...
Future Oncol. 2013;9(11):1609-1622. The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the ...
The article, “Development of an optogenetics tool, Opto‑RANK, for control of osteoclast differentiation using blue light,” was published in Scientific Reports at DOI: 10.1038/s41598-024 ...
"We were pleased to see that iSN40 not only promoted bone formation by osteoblasts but also inhibited osteoclast differentiation, which could have a major impact on preventing bone loss in ...
Juvenile Paget's disease belongs among the disorders characterized by excessive signaling along the pathway involving osteoclast differentiation factor, RANK, and nuclear factor-κB and leading to ...
During osteoclast differentiation, Ctdnep1 expression remains consistent, yet its depletion results in heightened osteoclast formation and activity. Mechanistically, Ctdnep1 demonstrates a ...
Kodama, H, Nose, M, Niida, S, Yamasaki, A. Essential role of macrophage colony-stimulating factor in the osteoclast differentiation supported by stromal cells. J Exp Med 1991;173:1291-1294.