During osteoclast differentiation, Ctdnep1 expression remains consistent, yet its depletion results in heightened osteoclast formation and activity. Mechanistically, Ctdnep1 demonstrates a suppressive ...

A representative micrograph of osteoclast differentiation and activity in response to irradiation with blue light. Numerous small pits formed on the bone-like substrate in the half of the well that ...

The Discovery of New Members of the TNF Receptor and Ligand Families and Their Relationship to Osteoclasts and Bone Metabolism Binding of RANKL to RANK initiates a signaling cascade, which includes ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Osteoporosis, a condition characterized by porous and fragile bones, poses a significant threat to skeletal health. As the very framework of the human body, bones provide crucial structural support.