Panelists discuss how the pathophysiology of pulmonary arterial hypertension involves complex mechanisms across multiple genetic and treatment pathways, with over 20 identified genes and four ...

Without effective treatment, pulmonary arterial hypertension results in high morbidity and mortality. This review discusses the pathogenesis of the disorder, the thorough clinical evaluation requir ...

Biochemical, genetic, and clinical evidence indicates that smooth-muscle proliferation around small pulmonary vessels is an essential part of the pathogenesis of pulmonary hypertension. Mutations i ...

The pulmonary vasculature is the exclusive target of disease in PPH, although its pathogenesis remains speculative. The most widely accepted mechanism suggests that PPH is a disease of predisposed ...

Investigators provide recent information on the classification, pathophysiology, diagnosis, and treatment of pulmonary arterial hypertension, focusing specifically on its impact on women.

Pulmonary arterial hypertension (PAH) is a disease characterized by increased pulmonary vascular resistance. 1,2 Symptoms at presentation include shortness of breath, fatigue, chest pain, or ...

Shares of Insmed jumped Tuesday after the biopharmaceutical firm reported positive results from a Phase 2 trial for its treatment of pulmonary arterial hypertension.

Pulmonary arterial hypertension (PAH) is a rare and severe lung disease with a life-threatening prognosis. After several positive trials, a recent study has confirmed the efficacy of a biotherapy ...

Charles Burger, MD: Pulmonary hypertension really refers to a state where the right heart is generating high pressures to circulate the blood through the lung. Pulmonary arterial hypertension is a ...

Read a review that discusses the pathogenesis and classification, clinical manifestations, diagnostic assessment, prognosis, and therapeutic strategies associated with pulmonary hypertension.