Australia's drug regulator has issued a safety warning over the medicine Phenergan and related products containing the antihistamine drug promethazine. The Therapeutic Goods Administration said ...

Codeine phosphate 10mg, promethazine HCl 6.25mg; per 5mL; syrup; contains alcohol 7%. Risk of life-threatening respiratory depression and death related to ultra-rapid metabolizers of codeine (esp.

Promethazine HCl 6.25mg, dextromethorphan HBr 15mg; per 5mL; liq; contains alcohol 7%. Dextromethorphan is an antitussive agent and, unlike the isomeric levorphanol, it has no analgesic or ...

The pharmacokinetics of promethazine administered in oral syrup and rectal suppositories were highly variable, but, in general, the suppositories produced a lower C max and later t max than the syrup.