We each get two copies of every gene - one copy from each of our parents. But what happens when one of these genes has been "turned off", or imprinted, and the remaining gene is defective?

People with Prader-Willi syndrome still carry the requisite genes from their mother, but those genes are naturally silenced in healthy people through a mechanism called imprinting. "There are many ...

Prader-Willi syndrome (PWS) is a rare genetic disease that causes ... those genes are naturally silenced via a mechanism called imprinting. “For most of our genes, we inherit one copy from our father ...

Federal regulators are clearing a first-of-its-kind treatment for symptoms of a rare neurodevelopmental disorder that is ...

You're not an equal product of both parents' genes. Genomic imprinting, a process whereby only one gene copy is expressed, not only exists but, combined with mutations, may lead to disease.

The United States Food and Drug Administration (US FDA) has approved VYKAT™ XR, a significant milestone as the first approved treatment for hyperphagia in Prader-Willi syndrome (PWS).

Clearance of Vykat unlocks what analysts anticipate will be a lucrative market opportunity for Soleno Therapeutics.

The FDA has approved Vykat XR (diazoxide choline) for the treatment of hyperphagia in adults and pediatric patients 4 years ...

Diazoxide choline is the first drug indicated for hyperphagia in the rare genetic disorder. Prior to approval, people with ...

The FDA has approved the first therapy to address hyperphagia for children and adults aged 4 years and older with ...