Muscle-cell necrosis and infiltration of macrophages are characteristic features of muscle-biopsy specimens from patients with statin-associated autoimmune myopathy. Hematoxylin and eosin staining ...

"Immune-mediated necrotizing myopathy is a rare group of debilitating myopathies characterized by symmetrical proximal muscle weakness that has a subacute onset and myofiber necrosis without ...

Constant muscle pain in a proximal distribution is often characteristic of inflammatory myopathies such as polymyositis and dermatomyositis, whereas episodic myalgias after exercise arise ...

The onset is usually insidious and painless and is characterized by progressive symmetric proximal muscle weakness during the course of 3 to 6 months. 3 Patients frequently complain of difficulty ...

In rare instances, however, the medication causes statin-triggered autoimmune myopathy, a condition characterized by proximal muscle weakness, prominent necrosis of muscle fibers (detected on ...

As much as 43% of patients with systemic sclerosis demonstrate evidence of myopathy, while those with proximal weakness and higher creatine kinase exhibit worse function and survival, according to ...

Did you know that certain medications can cause symptom of 'Proximal myopathy'. Find these drugs listed on the page and be warned of similar symptoms as possible side-effects.

STATINS side effects can include a whole host of symptoms. Experiencing problems with your muscles including a condition known as myopathy may be caused by taking the drug.

Immune-mediated necrotizing myopathy typically presents with progressive symmetrical proximal muscle weakness and myalgias, although some cases can present with respiratory and esophageal muscle ...

Proximal myopathy causes difficulty rising from a low chair, climbing steps, lifting objects and combing hair. Fatigue, myalgia, and muscle cramps may also be present.

Background: Many patients taking statins often complain of muscle pain and weakness. The extent to which muscle pain reflects muscle injury is unknown. Methods: We obtained biopsy samples from the ...

Practically all types of myopathy result in weakening and atrophy of skeletal muscles – particularly those closest to the center of the body (also known as the proximal muscles), such as the ...