She had swelling in both legs and ankles, and her motor strength in all extremities was 2/5, with proximal muscle weakness. Laboratory analysis showed elevated creatine kinase and myoglobin.

A 44-year-old woman with rheumatoid arthritis was evaluated because of proximal muscle weakness and myalgia. She had difficulty raising her arms above her head. Diagnostic tests were performed.

What is the differential diagnosis for a formerly active and healthy 70-year-old woman with worsening proximal weakness, torticollis, and a widespread raised red rash across her cheeks bilaterally?

Mild weakness was noted in the intrinsic hand muscles and proximal muscles of the arms and legs. Deep-tendon reflexes were asymmetrically brisk in the arms and normal in the legs. The plantar ...

In patients with proximal muscle weakness, the need for reflexive EMG followed by biopsy is negated if there is (1) presence of colchicine, (2) creatinine clearance <50 mL/min with or without ...

Muscle weakness is a common presenting symptom in patients with DM, with a subacute onset with gradually progressive symmetric proximal muscle weakness involving the shoulders, hips, and neck muscles.

The most prominent manifestations of SMA are proximal muscle weakness and atrophy. However, the phenotypic classification should not be taken as compartmentalizing the types into discrete categories.

Muscle weakness is more common in men, but if women experience it, it will mainly affect the proximal muscles (those closest to the center of the body). What causes dermatomyositis?

Immune-mediated necrotizing myopathy typically presents with progressive symmetrical proximal muscle weakness and myalgias, although some cases can present with respiratory and esophageal muscle ...

The muscle inflammation from PM manifests as muscle weakness, and most commonly affects the proximal muscles (the hips and thighs in the legs, and the upper arms, shoulders and neck in the upper ...

This is a milder form of SMA that typically develops after the age of 21 and is associated with mild to moderate proximal muscle weakness. Other, less common forms of SMA exist, but they occur due ...