Testosterone replacement therapy (TRT) reduces mortality risk by nearly 50% in men with Klinefelter syndrome (KS), bringing their survival rates closer to those of men from the general population. Men ...

Men with Klinefelter syndrome (KS) showed an increased risk for metabolic conditions such as type 2 diabetes (T2D) and obesity-related disorders, regardless of diagnosis and treatment status.

SMALL testes and aspermia are both characteristic features of Klinefelter's syndrome, and histological examination of the testes usually shows a lack of active spermatogenesis. Biopsies on testes ...

A group of international researchers has uncovered evidence of a super rare genetic condition that gives men an extra X chromosome, reporting the oldest clinical case of Klinefelter Syndrome to date.

THE tubules in the adult testis are characteristically totally hyalinized in Klinefelter's syndrome. But non-hyalinized tubules are often found in biopsies of reasonable size. Spermatogenesis may ...