The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

First discovered as proteins found on synaptic vesicles and at the presynaptic plasma membrane, SNAREs are members of a family of highly conserved proteins that reside on vesicles (v-SNAREs ...

Scientists use this protein as an indicator because it hangs out on the synaptic vesicles that store your neurotransmitters; generally, the more SV2A in your brain, the more synapses they can ...

However, the intricate mechanisms governing these processes have remained elusive due to the presence of multiple functional domains within Munc13, each playing distinct roles in neurotransmitter ...

The study introduces new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment. This ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ... the presynaptic neuron and restored inside a vesicle ready to be used again.