A recent study published in Psychophysiology provides new insights into how stimulating the vagus nerve through the ear might ...

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

A GROUNDBREAKING study has identified rare genetic variants in the ITSN1 gene that increase Parkinson’s disease risk by up to tenfold and reveal unexpected links to autism spectrum disorder (ASD), ...

First discovered as proteins found on synaptic vesicles and at the presynaptic plasma membrane, SNAREs are members of a family of highly conserved proteins that reside on vesicles (v-SNAREs ...

Clathrin-mediated endocytosis (CME) plays a crucial role in synaptic vesicle trafficking, and it has been hypothesized that CME impairment contributes to neuropathology related to schizophrenia.

By immunofluorescence microscopy, neuroligin induced accumulation of the characteristic synaptic vesicle proteins synapsin, synaptotagmin and synaptophysin, as well as the synaptic scaffolding ...

The study introduces new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment. This ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ... the presynaptic neuron and restored inside a vesicle ready to be used again.