How to Plant, Grow, and Care for a Toothache Plant. Derek Carwood. Tue, January 31, 2023 at 5:12 PM UTC. 4 min read.

Vastly larger than toothache plant is Hercules’ club, also called toothache tree. This cold-hardy native species (Zanthoxylum clava-hercules) ranges from a 10-foot shrub to a 25-foot tree.