Nature

TRH-Receptor-Type-2-Deficient Mice are Euthyroid and Exhibit Increased Depression and Reduced Anxiety Phenotypes

Thyrotropin-releasing hormone (TRH) is a neuropeptide that initiates its effects in mice by interacting with two G-protein-coupled receptors, TRH receptor type 1 (TRH-R1) and TRH receptor type 2 ...
The New England Journal of Medicine

A Family with Complete Resistance to Thyrotropin-Releasing Hormone

We report on a family with recessive resistance to the action of thyrotropin-releasing hormone (TRH) due to a nonsense homozygous mutation in the TRH receptor (TRHR) gene (p.R17X). We examined the in ...
Daily Emerald

Thyrotropin (TRH) Peptide: A Multidisciplinary Approach to its Research Implications

Thyrotropin-releasing hormone (TRH) is a small yet highly significant tripeptide consisting of the amino acids pyroglutamate, histidine, and proline. First identified in the hypothalamus, TRH was ...
Nature

CREB/TRH pathway in the central nervous system regulates energy expenditure in response to deprivation of an essential amino acid

In the central nervous system (CNS), thyrotropin-releasing hormone (TRH) has an important role in regulating energy balance. We previously showed that dietary deprivation of leucine in mice increases ...
The Business Journals

TRH Inspired relocates to larger space

To continue reading this content, please enable JavaScript in your browser settings and refresh this page. TRH Inspired — short for The Royal Hawaiian — is themed ...