LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.
Lipid bilayers in mammalian membranes can have a more asymmetric composition than previously thought, new research shows. This lipid abundance asymmetry is enabled by the unique properties of ...
Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered numerous age-related changes in the lipid metabolism of mice, across both organs and sexes. Among these changes ...
From combating cancer and infections to storing energy, lipid-protein interactions are critical to biological processes in cells. But the mechanisms that drive these interactions have historically ...
In a recent study published in the journal Nature Metabolism, a team of researchers conducted detailed longitudinal profiling and analysis of the lipidome using plasma samples from over a hundred ...
Cholesterol is a waxy substance present in our bloodstream that plays a crucial role in forming healthy cells. However, elevated cholesterol levels can lead to various health issues. In this article, ...
LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...
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Understanding cholesterol and health information

New insights are challenging what many people believe about cholesterol. Here is what actually matters for your health.
LNPs consist of ionizable lipids, which are critical for encapsulating RNA and enabling cellular uptake. Helper lipids contribute to the structural integrity and fusion with cell membranes.
FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...