Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the ...

The retromer complex controls protein sorting, transport, and disposal via the endolysosome system. It goes awry in neurodegenerative diseases, but how so remains unclear. Metabolism breaks down in ...

To age or not to age! How does aging affect organisms on a cellular level? What mechanisms help cells survive self-inflicted or external harm? It is known that lysosomes - critically important ...

October 24, 2025) Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate ...

Neuronal Ceroid Lipofuscinosis are a group of devastating neurodegenerative lysosomal storage disorders that begin in childhood. Mutations in CLN3 gene lead to a NCL called Batten disease, ...

Mitochondria are the main producers of energy in cells, and lysosomes recycle cellular debris that accumulates during normal function of our cells. Neurons are highly dependent on energy production by ...

Scientists studying tiny roundworms have uncovered how the secrets of a long life can be passed from parents to their offspring — without changing DNA. The discovery shows that when certain cellular ...

An RNAi based genetic screen and subsequent analyses reveal how dyneins and small GTPases coordinate autophagosome positioning at the ncMTOC in fat cells, advancing understanding of autophagic vesicle ...

Scientists have uncovered a new mechanism by which mutations in a gene parkin contribute to familial forms of Parkinson's disease. The discovery opens a new avenue for Parkinson's therapeutics, ...