Biotech company Colossal Biosciences said it has brought back the dire wolf, an animal that went extinct 10,000 years ago, through its de-extinction process.

For the first time in over 10,000 years, the howl of a dire wolf is echoing once more—this time, from within a secretive nature preserve in the United States. The predator, long thought extinct and famously mythologized in pop culture like Game of Thrones, is back, thanks to genetic engineering.