Journal of Neurology, Neurosurgery and Psychiatry (JNNP)

Current Issue

Short report: Cluster analysis showed long-term cognition can be predicted by looking at regional grey matter atrophy in the ...
BMJ

Distinct behavioural profiles in frontotemporal dementia and semantic dementia

OBJECTIVE To test predictions that frontotemporal dementia and semantic dementia give rise to distinct patterns of behavioural change. METHODS An informant based semistructured behavioural interview, ...
BMJ

The impact of delays in computed tomography of the brain on the accuracy of diagnosis and subsequent management in patients with minor stroke

Correspondence to: Professor J Wardlaw, Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK; jmw{at}skull.dcn.ed.ac.uk Objectives: To determine the ...
BMJ

Fluctuating cognition in dementia with Lewy bodies and Alzheimer’s disease is qualitatively distinct

2 Department of Psychology, The University of Melbourne, Parkville, Australia 3 Department of Psychiatry, The University of Melbourne, Parkville, Australia Correspondence to: Michael M Saling ...
BMJ

Fixed and dilated pupils after trauma, stroke, and previous intracranial surgery: management and outcome

OBJECTIVES To clarify whether different causative events (trauma, stroke, intracranial surgery), time of intervention, and treatment mode influence outcome, patients with fixed and dilated pupils ...
BMJ

Postinfectious brainstem encephalitis associated with SARS-CoV-2

Correspondence to Dr Anthony Khoo, Department of Neurology, University College London Hospitals NHS Foundation Trust National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK ...
BMJ

Impact of early intervention on outcome following mild head injury in adults

Background: The impact of mild head injury is variable and determinants of outcome remain poorly understood. Results of previous intervention studies have been mixed. Objectives: To evaluate the ...
BMJ

Hippocampal dysfunction defines disease onset in Huntington's disease

Background Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterised by a triad of motor, psychiatric and cognitive deficits with the latter classically attributed to ...
BMJ

Neurological immune-related adverse events with checkpoint inhibitor therapy: challenges for the neurologist

Immune checkpoint inhibitors (ICI) have had a dramatic effect on cancer outcomes with their use increasing as indications expand. Despite impressive efficacy across a range of tumour types, their role ...
BMJ

Visuospatial functions in atypical parkinsonian syndromes

Objectives: Visuospatial deficits have been occasionally reported but never systematically studied in atypical parkinsonian syndromes. The interpretation of existing studies is complicated by the ...
BMJ

Interleukin 18 gene polymorphisms predict risk and outcome of Alzheimer’s disease

Background and aim: Inflammation has been extensively implicated in the pathogenesis of Alzheimer’s disease (AD). Although there is evidence of a key role for cytokines in neuroinflammation processes, ...