BACKGROUND: Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractility and high ...

Cardiac intensive care units are specialized, high-acuity, and resource-intensive environments for the care of critically ill ...

Resources for observational comparative research have expanded enormously in recent years to include very large sources of ...

Artificial intelligence shows promise for improving care for peripheral artery disease through earlier detection, improved ...

BACKGROUND: The optimal transfusion strategy in patients with acute myocardial infarction (AMI) and anemia may be influenced by sex differences in pathophysiology and cardiovascular outcomes. The ...

Background: Lipoprotein(a) [Lp(a)] is a risk factor for coronary heart disease. Whether baseline Lp(a) identifies higher risk patients who derive more benefit from evolocumab is not established in a ...

Spontaneous coronary artery dissection (SCAD) is an important cause of myocardial infarction associated with pregnancy (P-SCAD). 1–3 It is also an understudied cause of maternal death. 4 The present ...

We performed simultaneous (radial) arterial and (mixed) venous blood gas lactate measurements in 1526 patients at a quaternary cardiac intensive care unit (ICU; both surgical [N=1356, 86%] and ...

Metabolic remodeling, marked by maladaptive shifts in substrate use and energy production, is a hallmark of pathologic cardiac hypertrophy. Yet the mechanisms linking stress signaling to impaired ...

Air pollution is a risk factor for dementia, but its role in early cognitive dysfunction is not clear. We aimed to investigate the association of air pollution with cognitive function, and the role of ...

Background: Chronic insomnia affects up to one-third of adults, and over-the-counter melatonin is increasingly promoted as a “cardiometabolic-friendly” sleep aid. Robust data on its long-term ...

…Things are not always what they seem; the first appearance deceives many; the intelligence of a few perceives what has been carefully hidden…. A 66-year-old man with a history of previous anterior ...