The Tp-e interval, and Tp-e/QT Tp-e/QTc ratios were significantly prolonged in patients with wild-type ATTR-CM compared to healthy people. Electrocardiographic (ECG) parameters are prolonged in ...

Spesolimab is a humanized monoclonal immunoglobulin G1 antibody and is the first therapy to target the IL-36 pathway, a key driver of GPP disease processes. Spesolimab has an acceptable safety profile ...

The physical environment was the only significant predictor of participation, explaining 34.1% of the variance. Children with Duchenne muscular dystrophy (DMD) participate less in daily life than do ...

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare acquired autoimmune neurological disorder in which both T-cell-mediated and humoral immune mechanisms target healthy myelinated ...

Individuals with advanced liver disease may also experience significant weight loss due to nausea and poor appetite. Candidates for liver transplantation may need to gain weight to optimize surgical ...

In CIDP, SOC therapies (immunoglobulins/corticosteroids) are burdensome, have variable efficacy, and significant side-effects. Two phase 3 clinical trials, MOBILIZE ...

Inebilizumab-cdon (Uplizna ®) has received US Food and Drug Administration (FDA) approval for the treatment of adults with generalized myasthenia gravis (MG) with antibodies against the acetylcholine ...

Long-term ruxolitinib use may lead to invasive fungal sinusitis, according to a new case study published in the Journal of Medical Case Reports. “Surgical treatment in combination with antifungal and ...

Several factors can contribute to the suppression of bone marrow erythropoiesis in infants with HDFN, including maternal antibodies, intrauterine transfusion, and simple transfusion. The suppression ...

Gastrointestinal involvement in systemic mastocytosis (SM) is a common complication and often leads to endoscopic findings. Gastrointestinal (GI) symptoms are the second most frequent clinical ...

Professor Aya Abrahamov and two Palestinian women with Gaucher disease share a light moment at Shaare Zedek Medical Center in Jerusalem, Israel (Photo by Ari Zimran) Shaare Zedek’s Gaucher unit is the ...

Intravenously administered zaltenibart was shown to be safe and effective in phase 2 clinical trials. Enrollment is under way to recruit patients for a phase 3 study designed to assess intravascular ...