Only when these difficulties have been overcome, and the systems biochemistry and structural biology of chromosomes have been fully elucidated, will the last word on chromatin have been spoken.

Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to chromatin remodeling, a process implicated in cancer and developmental ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

We specialize in high throughput top down liquid chromatography-mass spectrometry. This allows us to study chromatin biology with proteoform level specificity and observe quantitative changes to ...

View Full Profile. Learn about our Editorial Policies. Lis and Gilmour focused on identifying proteins that bound to specific chromatin sites to understand the mechanisms of gene regulation. To do so, ...

Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...