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Oncogenic YAP accelerates S-phase entry by shortening G1, leading to replication stress and sensitivity to CHK1 inhibition.
New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.
Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the ...
Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...
Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...
Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...
Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...
Scientists have identified two proteins involved in regulating chromatin remodelling which could be promising therapeutic ...
In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal ...
An atom consists of a heavy center, called the nucleus, made of particles called protons and neutrons. An atom has lighter particles called electrons that you can think of as orbiting around the ...
Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host's cellular machinery to make new copies of themselves. Herpes simplex ...
Red cell nucleus, green cytoskeleton: in microscopic images like this one, the AI developed at PSI recognizes the finest changes in chromatin – and thus genetic disorders.