Specialized DNA repair pathways handle distinct threats, from single-strand nicks to double-strand breaks. These coordinated strategies ... Others check whether small molecule drugs can disrupt ...

The efficacy of radiotherapy is largely limited by the DNA damage repair capacity of tumor cells. When ionizing radiation ...

The native structure of genomic DNA can be damaged in many ... nucleotide excision repair; pol η, polymerase η; SSB, single-strand break; TCR, transcription-coupled repair.

Single-stranded DNA is less common than double-stranded DNA. It is often found in some viruses and plays a key role in certain biological processes, such as cell replication or repair. Single-stranded ...

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in ...

identifying double-strand breaks in DNA and then recruiting a different type of protein, known as 53BP1, to repair them. This can lead to runaway cellular replication—cancer. Counter-intuitively ...

complexes involved in double-strand break and stalled replication fork repair, and on complexes mediating the meiotic recombination pathway (with Scott Keeney, MSKCC). In addition, research is focused ...

Epigenome-targeted DNA repair can help organisms ... lead to false negatives for domain presence in a single species. For example, fragmentation during genome assembly could lead to edge cases where ...

ROCHESTER, Michigan – Wright State baseball's Gus Gregory broke the program's single-game RBI record as the Raiders defeated Oakland 24-12 on Friday afternoon, securing the series win. Gregory, a ...