However, once the average gene length reaches 1,500 nucleotides, the proteins decouple from the multiplicative process of gene growth, and the average protein length stabilizes after the onset of the ...

Aberrations in chromatin organization are implicated in various diseases, particularly cancer. While Hi-C is the gold standard for mapping chromosomal conformations, it has significant limitations: it ...

Citation Format: Brian Sun Liu, Mengran Zhang, Takeshi Sugio, Mohammad Shahrokh Esfahani. Mathematical modeling of cell-free DNA fragmentation to map chromatin landscapes in health and cancer ...