The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

QIAGEN N.V. (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced a series of product and partnership updates designed ...

These three-stranded nucleic acid structures, composed of an RNA:DNA hybrid and a displaced ... and facilitating repair through homologous recombination. However, when dysregulated, R-loops ...

Sydney: Australian researchers have found that DNA repair may determine how cancer ... by radiation was repaired by a method called homologous recombination, they found that cancer cells died ...

“We now have several biomarkers to guide therapy in advanced prostate cancer such as homologous recombination DNA repair defects for PARP inhibitors, defective mismatch repair for pembrolizumab ...

The company’s gold-standard Genomic Instability Score (“GIS”) to determine Homologous Recombination ... have lost the ability to repair double-stranded DNA breaks, resulting in increased ...

PARPi, by inhibiting single-strand DNA break repair, are synthetically lethal in homologous recombination (HR)-deficient cancer cells, highlighting the importance of identifying strategies to exploit ...

April 9, 2025 First-line talazoparib plus enzalutamide versus placebo plus enzalutamide in men with metastatic castration-resistant prostate cancer and homologous recombination repair ... Rare ...