Idiopathic pulmonary fibrosis (IPF) is characterized by a progressive decline in lung function, worsening quality of life, and high mortality. However, the rate and pattern of progression of IPF ...

Fibrosis is characterized by the excessive or abnormal accumulation of extracellular matrix ... LOXL2 inhibitor for the treatment of idiopathic pulmonary, liver and kidney fibrosis, and PAT ...

The term “progressive pulmonary fibrosis” or “PPF” is generally used to describe progressive lung fibrosis in an individual with an interstitial lung disease (ILD) other than idiopathic ...

It is characterized by the accumulation of extracellular matrix in the skin and internal ... and some degree of pulmonary fibrosis is found in the majority of patients postmortem.

is a progressive fibrotic lung disease of unknown cause. It remains incurable and has a poor prognosis for many patients, with a median survival of 3-5 years from diagnosis. For more information on ...

The UAB ILD Center offers clinical trial enrollment for patients with idiopathic pulmonary fibrosis and other forms of diffuse parenchymal lung disease as part of a multidisciplinary and integrated ...

Hepatic fibrosis is a reversible wound healing response characterized by accumulation of extracellular matrix (ECM), or "scar," that follows chronic but not self-limited liver disease. The ECM ...

The relationship of fibrosis of the extracellular matrix with tumors ... chemotherapy with a drug currently used against ...

Everyone gets tired, but you usually feel better after a good night’s sleep. People with idiopathic hypersomnia (IH), however, feel excessively sleepy all the time, even after a full night of rest.

Idiopathic hypersomnia (IH) is, in many ways, a mystery. Its cause is unknown. Only one FDA-approved treatment exists. Even diagnosing this disorder, which brings excessive sleepiness in the ...