A new article in the journal Nucleic Acid Therapeutics addresses the recognition by the U.S. Food and Drug Administration that immunogenicity assays may be necessary to measure immune responses to ...

Download Cerba Research's new report to discover how to overcome immunogenicity and safety challenges in oncology.

Cellular immunogenicity and immunotoxicity assays help scientists design, validate, and translate therapeutic research into treatments that weaponize the immune response against cancer.

Serum samples for anti-panitumumab antibody testing were collected from mCRC patients enrolled in 4 panitumumab clinical trials (20050184, 20060277, 20050181, and 20050203). Patients in these ...

Immunogenicity testing focuses on detecting small amounts of antidrug antibodies, so assay sensitivity needs to be carefully determined. In contrast, PK analysis is generally not required for ...

In the vaccine efficacy and preclinical safety space, this includes immunogenicity assays, neurovirulence testing, antibody-dependent enhancement and vaccine-associated enhanced disease models and ...

Comparing the immunogenicity of currently used TNF-α ... making it difficult or impossible for a drug-sensitive assay to detect anti-etanercept antibodies. One approach to overcome this problem ...

AC Immune Reports First Quarter 2025 Financial Results and Provides a Corporate Update Continuing to advance clinical active immunotherapy portfolio for precision prevention of neurodegenerative ...

Enables the tiered approach for screening, confirmatory, titer, and neutralizing immunogenicity assays to support in vivo study immune response endpoints. Assesses run performance against pre-defined ...

In this webinar brought to you by Lonza, Ethan Shelkey and Aurita Menezes will discuss the effects of donor variability in cell-based assays for measuring drug immunogenicity and immunotoxicity. Lab ...