Serum samples for anti-panitumumab antibody testing were collected from mCRC patients enrolled in 4 panitumumab clinical trials (20050184, 20060277, 20050181, and 20050203). Patients in these ...

CDMOs are crucial partners in alum-based vaccine production, managing aseptic filling with precision and efficiency.

Risk mitigation through immunogenicity assays studies The development of SARS-CoV-2 vaccines pushed efforts to generate an array of standardised assays that could be used to rapidly measure ...

Immunogenicity testing focuses on detecting small amounts of antidrug antibodies, so assay sensitivity needs to be carefully determined. In contrast, PK analysis is generally not required for ...

The fully human nature of panitumumab was expected to decrease the rate of immunogenicity compared ... Intersection of the assay threshold with the rabbit polyclonal anti-panitumumab antibody ...

Sarfaraz K. Niazi, PhD, shares his latest citizen's petition to the FDA, calling on the agency to waive clinical efficacy ...

Despite harboring the highest tumor mutational burden of all cancers, basal cell carcinomas (BCCs) have low immunogenicity. Loss of human leukocyte antigens class I (HLA-I) components is ...

DELRAY BEACH, Fla., April 21, 2025 /PRNewswire/ -- The global Cell Based Assays Market, valued at US$17.29 billion in 2024, is forecasted to grow at a robust CAGR of 9.1%, reaching US$17.84 ...

As immune-modulating therapies surge forward, with over 4,000 immune modulators in development globally, scientists are refining assay technologies that maintain the complexity of patient-specific ...

It can involve screening large libraries of chemicals for a particular biological activity in high-throughput screening assays.