Serum samples for anti-panitumumab antibody testing were collected from mCRC patients enrolled in 4 panitumumab clinical trials (20050184, 20060277, 20050181, and 20050203). Patients in these ...

CDMOs are crucial partners in alum-based vaccine production, managing aseptic filling with precision and efficiency.

Risk mitigation through immunogenicity assays studies The development of SARS-CoV-2 vaccines pushed efforts to generate an array of standardised assays that could be used to rapidly measure ...

Immunogenicity testing focuses on detecting small amounts of antidrug antibodies, so assay sensitivity needs to be carefully determined. In contrast, PK analysis is generally not required for ...

App Note / Case Study Automation of a Homogeneous Proximity Assay for Immunogenicity Testing of Biological Drug Products Several challenges have surfaced during clinical evaluation of biological drug ...

Demonstrated 24-month stability validation of XPro™ for phase III readiness and commercial supply chain modeling & announced development of novel immunogenicity assay.

The fully human nature of panitumumab was expected to decrease the rate of immunogenicity compared ... Intersection of the assay threshold with the rabbit polyclonal anti-panitumumab antibody ...

These lead compounds affected the immunogenicity (the ability to elicit ... We hope that this assay can help identify other drugs that, at low doses, can potentiate T-cells to better kill tumor ...

The Biden administration's FDA "seemed to be inert" on the issue, and even "obstructionist," after Congress removed mandatory ...

Emulate, Inc., a leading provider of next-generation in vitro models, today welcomed the U.S. Food and Drug Administration’s (FDA) newly announced plan to reduce reliance on animal testing in ...

These names in the biotech sector are seeing a substantial increase in search activity today, as determined by InvestingChannel. They include: ...