Researchers at the Francis Crick Institute have shown that the Cryptosporidium parasite exports a protein into infected ...

Numerous studies have suggested the cultivation of cells derived from intestinal organoids as two-dimensional (2D) monolayers ...

Background IBD is a chronic inflammatory condition driven by complex genetic and immune interactions, yet preclinical models ...

Intestinal stem cells continuously self-renew by dividing and differentiate into the specialised cells of the intestinal epithelium, which renews throughout life.

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have ...

The risk of developing blood cancer increases with age. The finding that a molecule from gut bacteria plays a part points to ...

Obesity can lead to a chronic inflammatory state within the body. What drives this inflammation? Does inflammation, in turn, ...

Discover a study where researchers have discovered a myeloid-derived antigen-presenting cells population essential for peripherally induced regulatory T cells.

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to ...

Specific host factors, such as immune cell activity, sex hormones and microbiota composition, influence the ability of Staphylococcus aureus bacteria to colonize the gut of mice.

In recent years our traditional understanding of both macrophages and neutrophils has been greatly challenged. Previously thought to promote inflammatory ...