Researchers at the Francis Crick Institute have shown that the Cryptosporidium parasite exports a protein into infected ...

Numerous studies have suggested the cultivation of cells derived from intestinal organoids as two-dimensional (2D) monolayers ...

Background IBD is a chronic inflammatory condition driven by complex genetic and immune interactions, yet preclinical models ...

Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor ...

difficile infection. The white areas show the cells that line the intestine (epithelial cells). In red is the MHC-II protein, which helps activate the immune system, and in blue is the nucleus of ...

Fachi et al, Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection, Cell Host & Microbe (2025). DOI: 10.1016/j.chom.

Deciphering the gut biome's, including helminths', influence on human trained immunity will unlock novel immunotherapies harnessing the immune reprogramming potential of their secreted factors and ...

“This is particularly true of Candida,” which is a “lifelong colonizer of intestinal microbiota ... that facilitate adherence to epithelial cells) and a cytolytic toxin it produces ...

Research published in Oncotarget found that fasting reduces the polarization of M2-type tumor-associated macrophages in ... promotes regeneration of intestinal cells, it could also accelerate ...