Neuropeptide Y (NPY), a 36-amino-acid peptide widely expressed in the brain1 is involved in many physiological responses2, including hypothalamic control of food intake and cardiovascular ...

Not that kind of edible - this one's electronic DARPA has announced a research program to explore whether an "ingestible form factor" device can stimulate gut neurons to modulate stress responses, ...

What’s becoming clear is that obesity isn’t one disease — it’s many, said Jack Yanovski, a senior obesity researcher at the ...

Vykat XR is not a cure for the disease. Instead, it calms overactive neurons in the hypothalamus that release neuropeptide Y—one of the body's strongest hunger signals.

Neuropeptide Y belongs to the pancreatic polypeptide family, which activates the seven-transmembrane G protein-coupled receptors (GPCRs) Y1–Y6. [42] NPY is a potent orexigenic neuropeptide.

A new drug is helping families who've spent years padlocking fridges, chaining garbage cans, and hiding food as their children with Prader-Willi syndrome deal with unrelenting hunger.

Hepatic vein plasma neuropeptide Y was greater than arterial both at rest (119±5% of arterial, n=7) and after a meal (132±12%, n=7), with neuropeptide Y overflows of 6±2 and 11±2 pmol/min, ...

Cell culture studies demonstrate an increase in cardiac L-type Ca 2+ current (ICa,L) density on sympathetic innervation in vitro and suggest the effect depends on neurally released neuropeptide Y (NPY ...

Neuropeptide Y (NPY) (1) is highly expressed in the mammalian brain. Its pharmacological administration into the central nervous system reduces experimental anxiety in a wide range of animal models (2 ...

The influence of Neuropeptide-Y on coronary perfusion and arrhythmogenicity Professor Neil Herring (lead researcher) University of Oxford Start date: 01 April 2015 (Duration 5 years, 5 months) The ...

Leafcutter ants live in highly organized colonies where every ant has a job, and now researchers can flip those jobs like a switch. By manipulating just two neuropeptides, scientists can turn ...

The novel cue-induced analgesia paradigm allowed a compelling identification of a brainstem circuit element, i.e., somatostatin-expressing neurons within the ventrolateral periaqueductal grey that ...